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Research Article

Serum S100A6 Concentration Predicts Peritoneal Tumor Burden in Mice with Epithelial Ovarian Cancer and Is Associated with Advanced Stage in Patients

  • Bih-Rong Wei,

    Affiliation: Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

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  • Shelley B. Hoover,

    Affiliation: Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

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  • Mark M. Ross,

    Affiliation: Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia, United States of America

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  • Weidong Zhou,

    Affiliation: Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia, United States of America

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  • Francesco Meani,

    Affiliation: University of Brescia, Brescia, Italy

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  • Jennifer B. Edwards,

    Affiliation: Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

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  • Elizabeth I. Spehalski,

    Affiliation: Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

    Current address: Department of Molecular and Cellular Pathology, University of Michigan College of Medicine, Ann Arbor, Michigan, United States of America

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  • John I. Risinger,

    Affiliation: Anderson Cancer Institute, Memorial Health University Medical Center, Inc., Savannah, Georgia, United States of America

    Current address: Department of Obstetrics, Gynecology and Reproductive Biology, Michigan State University College of Human Medicine, Grand Rapids, Michigan, United States of America

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  • W. Gregory Alvord,

    Affiliation: Data Management Services, Inc., National Cancer Institute, Frederick, Maryland, United States of America

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  • Octavio A. Quiñones,

    Affiliation: Data Management Services, Inc., National Cancer Institute, Frederick, Maryland, United States of America

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  • Claudio Belluco,

    Affiliations: Centro di Riferimento Oncologico, IRCCS, National Cancer Institute, Aviano, Italy, Department of Haematology, Oncology, and Molecular Medicine, Istituto Superiore di Sanita, Rome, Italy

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  • Luca Martella,

    Affiliation: Centro di Riferimento Oncologico, IRCCS, National Cancer Institute, Aviano, Italy

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  • Elio Campagnutta,

    Affiliation: Centro di Riferimento Oncologico, IRCCS, National Cancer Institute, Aviano, Italy

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  • Antonella Ravaggi,

    Affiliation: University of Brescia, Brescia, Italy

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  • Ren-Ming Dai,

    Affiliation: Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

    Current address: Laboratory of Experimental Immunology, NCI Frederick, Frederick, Maryland, United States of America

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  • Paul K. Goldsmith,

    Affiliation: Antibody and Protein Purification Unit, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

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  • Kevin D. Woolard,

    Affiliation: Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

    Current address: Neuro-Oncology Branch, Center for Cancer Research, NCI, Bethesda, Maryland, United States of America

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  • Sergio Pecorelli,

    Affiliation: University of Brescia, Brescia, Italy

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  • Lance A. Liotta,

    Affiliation: Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia, United States of America

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  • Emanuel F. Petricoin III,

    Affiliation: Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia, United States of America

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  • R. Mark Simpson mail

    ms43b@nih.gov

    Affiliation: Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America

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  • Published: October 30, 2009
  • DOI: 10.1371/journal.pone.0007670

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