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Research Article

Systemic Inhibition of NF-κB Activation Protects from Silicosis

  • Michelangelo Di Giuseppe,

    Affiliation: Division of Occupational and Environmental Medicine, Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Federica Gambelli,

    Affiliation: Division of Occupational and Environmental Medicine, Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Gary W. Hoyle,

    Affiliation: Department of Environmental and Occupational Health Sciences, School of Public Health and Informational Sciences, University of Louisville, Louisville, Kentucky, United States of America

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  • Giuseppe Lungarella,

    Affiliation: Department of Physiopathology, University of Siena, Siena, Italy

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  • Sean M. Studer,

    Affiliation: Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

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  • Thomas Richards,

    Affiliation: Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

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  • Sam Yousem,

    Affiliation: Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

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  • Ken McCurry,

    Affiliation: Department of Thoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

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  • James Dauber,

    Affiliation: Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

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  • Naftali Kaminski,

    Affiliation: Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

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  • George Leikauf,

    Affiliation: Division of Occupational and Environmental Medicine, Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Luis A. Ortiz mail

    lao1@pitt.edu

    Affiliations: Division of Occupational and Environmental Medicine, Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

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  • Published: May 25, 2009
  • DOI: 10.1371/journal.pone.0005689

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