Advertisement
Research Article

Breast Tumor Cells with PI3K Mutation or HER2 Amplification Are Selectively Addicted to Akt Signaling

  • Qing-Bai She,

    Affiliation: Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Sarat Chandarlapaty equal contributor,

    equal contributor Contributed equally to this work with: Sarat Chandarlapaty, Qing Ye

    Affiliation: Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Qing Ye equal contributor,

    equal contributor Contributed equally to this work with: Sarat Chandarlapaty, Qing Ye

    Affiliation: Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Jose Lobo,

    Affiliation: Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Kathleen M. Haskell,

    Affiliation: Department of Cancer Research, Merck Research Laboratories, West Point, Pennsylvania, United States of America

    X
  • Karen R. Leander,

    Affiliation: Department of Cancer Research, Merck Research Laboratories, West Point, Pennsylvania, United States of America

    X
  • Deborah DeFeo-Jones,

    Affiliation: Department of Cancer Research, Merck Research Laboratories, West Point, Pennsylvania, United States of America

    X
  • Hans E. Huber,

    Affiliation: Department of Cancer Research, Merck Research Laboratories, West Point, Pennsylvania, United States of America

    X
  • Neal Rosen mail

    rosenn@mskcc.org

    Affiliation: Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Published: August 26, 2008
  • DOI: 10.1371/journal.pone.0003065

Media Coverage of this Article

Found additional news media or blog coverage for the article? Please let us know.