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Research Article

Pre-Clinical Evaluation of a Novel Nanoemulsion-Based Hepatitis B Mucosal Vaccine

  • Paul E. Makidon equal contributor,

    equal contributor Contributed equally to this work with: Paul E. Makidon, Anna U. Bielinska

    Affiliations: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America, Unit for Laboratory Animal Medicine (ULAM), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Anna U. Bielinska equal contributor,

    equal contributor Contributed equally to this work with: Paul E. Makidon, Anna U. Bielinska

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Shraddha S. Nigavekar,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Katarzyna W. Janczak,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Jessica Knowlton,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Alison J. Scott,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Nicholas Mank,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Zhengyi Cao,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Sivaprakash Rathinavelu,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Michael R. Beer,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • J. Erby Wilkinson,

    Affiliation: Unit for Laboratory Animal Medicine (ULAM), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Luz P. Blanco,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Jeffrey J. Landers,

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • James R. Baker Jr mail

    jbakerjr@umich.edu

    Affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences (M-NIMBS), University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Published: August 13, 2008
  • DOI: 10.1371/journal.pone.0002954

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