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Research Article

Broad and Gag-Biased HIV-1 Epitope Repertoires Are Associated with Lower Viral Loads

  • Morgane Rolland,

    Affiliation: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • David Heckerman,

    Affiliation: Machine Learning and Applied Statistics Group, Microsoft Research, Redmond, Washington, United States of America

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  • Wenjie Deng,

    Affiliation: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Christine M. Rousseau,

    Affiliation: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Hoosen Coovadia,

    Affiliation: HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa

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  • Karen Bishop,

    Affiliation: HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa

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  • Philip J. R. Goulder,

    Affiliations: HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa, Nuffield Department of Medicine, Oxford University, Oxford, United Kingdom, Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

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  • Bruce D. Walker,

    Affiliations: HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa, Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

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  • Christian Brander,

    Affiliation: Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

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  • James I. Mullins mail

    To whom correspondence should be addressed. E-mail: jmullins@u.washington.edu

    Affiliation: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Published: January 09, 2008
  • DOI: 10.1371/journal.pone.0001424

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