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Open Access
Peer-reviewed
Research Article
Functional Inactivation of EBV-Specific T-Lymphocytes in Nasopharyngeal Carcinoma: Implications for Tumor Immunotherapy
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Jiang Li,
Affiliations State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Xue-hui Zeng,
Affiliation Institute of Molecular Immunology, School of Biotechnology, Technology University of Southern China, Guangzhou, China
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Hao-yuan Mo,
Affiliations Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Ulrika Rolén,
Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
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Yan-fang Gao,
Affiliations Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Xiao-shi Zhang,
Affiliations Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Qiu-yan Chen,
Affiliations Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Li Zhang,
Affiliations Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Mu-sheng Zeng,
Affiliations State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Man-zhi Li,
Affiliations State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Wen-lin Huang,
Affiliations State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Xiao-ning Wang,
Affiliation Institute of Molecular Immunology, School of Biotechnology, Technology University of Southern China, Guangzhou, China
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Yi-Xin Zeng ,
*To whom correspondence should be addressed. E-mail: maria.masucci@ki.se (MM); zengyxi@mail.sysu.edu.cn (YZ)
Affiliations State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Experimental Research, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Biotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China, Department of Radiotherapy, Cancer Center, Sun Yat-sen University, Guangzhou, China
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Maria G. Masucci
*To whom correspondence should be addressed. E-mail: maria.masucci@ki.se (MM); zengyxi@mail.sysu.edu.cn (YZ)
Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
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Functional Inactivation of EBV-Specific T-Lymphocytes in Nasopharyngeal Carcinoma: Implications for Tumor Immunotherapy
- Jiang Li,
- Xue-hui Zeng,
- Hao-yuan Mo,
- Ulrika Rolén,
- Yan-fang Gao,
- Xiao-shi Zhang,
- Qiu-yan Chen,
- Li Zhang,
- Mu-sheng Zeng,
- Man-zhi Li
- Published: November 7, 2007
- https://doi.org/10.1371/journal.pone.0001122