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Open Access
Peer-reviewed
Research Article
Mitochondrial DNA Variants of Respiratory Complex I that Uniquely Characterize Haplogroup T2 Are Associated with Increased Risk of Age-Related Macular Degeneration
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John Paul SanGiovanni ,
Contributed equally to this work with: John Paul SanGiovanni, Dan E. Arking
* E-mail: jpsangio@post.harvard.edu
Affiliation National Eye Institute (NEI)/National Institutes of Health (NIH), Bethesda, Maryland, United States of America
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Dan E. Arking ,
Contributed equally to this work with: John Paul SanGiovanni, Dan E. Arking
Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
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Sudha K. Iyengar,
Affiliation Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America
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Michael Elashoff,
Affiliation CardioDx, Palo Alto, California, United States of America
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Traci E. Clemons,
Affiliation The EMMES Corp., Rockville, Maryland, United States of America
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George F. Reed,
Affiliation National Eye Institute (NEI)/National Institutes of Health (NIH), Bethesda, Maryland, United States of America
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Alice K. Henning,
Affiliation The EMMES Corp., Rockville, Maryland, United States of America
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Theru A. Sivakumaran,
Affiliation Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America
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Xuming Xu,
Affiliation Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, United States of America
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Andrew DeWan,
Affiliation Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, United States of America
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Elvira Agrón,
Affiliation National Eye Institute (NEI)/National Institutes of Health (NIH), Bethesda, Maryland, United States of America
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Elena Rochtchina,
Affiliation Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Institute, University of Sydney, Sydney, Australia
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Carolyn M. Sue,
Affiliation University of Sydney Kolling Institute for Medical Research, Sydney, Australia
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Jie Jin Wang,
Affiliation Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Institute, University of Sydney, Sydney, Australia
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Paul Mitchell,
Affiliation Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Institute, University of Sydney, Sydney, Australia
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Josephine Hoh,
Affiliation Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, United States of America
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Peter J. Francis,
Affiliation Macular Degeneration Center, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America
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Michael L. Klein,
Affiliation Macular Degeneration Center, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America
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Emily Y. Chew,
Affiliation National Eye Institute (NEI)/National Institutes of Health (NIH), Bethesda, Maryland, United States of America
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Aravinda Chakravarti
Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
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Mitochondrial DNA Variants of Respiratory Complex I that Uniquely Characterize Haplogroup T2 Are Associated with Increased Risk of Age-Related Macular Degeneration
- John Paul SanGiovanni,
- Dan E. Arking,
- Sudha K. Iyengar,
- Michael Elashoff,
- Traci E. Clemons,
- George F. Reed,
- Alice K. Henning,
- Theru A. Sivakumaran,
- Xuming Xu,
- Andrew DeWan
- Published: May 12, 2009
- https://doi.org/10.1371/journal.pone.0005508