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Open Access
Peer-reviewed
Research Article
PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons
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Alison Wood-Kaczmar ,
Contributed equally to this work with: Alison Wood-Kaczmar, Sonia Gandhi
Affiliation Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom
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Sonia Gandhi ,
Contributed equally to this work with: Alison Wood-Kaczmar, Sonia Gandhi
Affiliations Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom, Medical Molecular Biology Unit, Institute of Child Health, London, United Kingdom
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Zhi Yao,
Affiliation Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom
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Andrey S. Y. Abramov,
Affiliation Department of Physiology, University College London, London, United Kingdom
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Erik A. Miljan,
Affiliation ReNeuron Ltd, Guildford, United Kingdom
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Gregory Keen,
Affiliation Eisai London Research Laboratories Ltd, London, United Kingdom
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Lee Stanyer,
Affiliation Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom
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Iain Hargreaves,
Affiliation Neurometabolic Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom
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Kristina Klupsch,
Affiliation Cancer Research United Kingdom, London, United Kingdom
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Emma Deas,
Affiliation Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom
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Julian Downward,
Affiliation Cancer Research United Kingdom, London, United Kingdom
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Louise Mansfield,
Affiliation Department of Neurodegenerative Disease, Institute of Neurology, London, United Kingdom
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Parmjit Jat,
Affiliation Department of Neurodegenerative Disease, Institute of Neurology, London, United Kingdom
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Joanne Taylor,
Affiliation Eisai London Research Laboratories Ltd, London, United Kingdom
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Simon Heales,
Affiliations Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom, Neurometabolic Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom
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Michael R. Duchen,
Affiliation Department of Physiology, University College London, London, United Kingdom
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David Latchman,
Affiliations Medical Molecular Biology Unit, Institute of Child Health, London, United Kingdom, Birkbeck, University of London, London, United Kingdom
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Sarah J. Tabrizi ,
¶These authors also contributed equally to this work.
Affiliation Department of Neurodegenerative Disease, Institute of Neurology, London, United Kingdom
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Nicholas W. Wood
* E-mail: n.wood@ion.ucl.ac.uk
¶These authors also contributed equally to this work.
Affiliation Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom
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PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons
- Alison Wood-Kaczmar,
- Sonia Gandhi,
- Zhi Yao,
- Andrey S. Y. Abramov,
- Erik A. Miljan,
- Gregory Keen,
- Lee Stanyer,
- Iain Hargreaves,
- Kristina Klupsch,
- Emma Deas
- Published: June 18, 2008
- https://doi.org/10.1371/journal.pone.0002455