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Open Access

Peer-reviewed

Research Article

Computational Design of a pH Stable Enzyme: Understanding Molecular Mechanism of Penicillin Acylase's Adaptation to Alkaline Conditions

  • Dmitry Suplatov,

    Affiliation Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia

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  • Nikolay Panin,

    Affiliation Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia

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  • Evgeny Kirilin,

    Affiliation Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia

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  • Tatyana Shcherbakova,

    Affiliation Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia

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  • Pavel Kudryavtsev,

    Affiliation Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia

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  • Vytas Švedas

    vytas@belozersky.msu.ru

    Affiliation Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia

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