Ethanol-Induced Transcriptional Activation of Programmed Cell Death 4 (Pdcd4) Is Mediated by GSK-3β Signaling in Rat Cortical Neuroblasts

Amanjot Kaur Riar; Madhusudhanan Narasimhan; Mary Latha Rathinam; Dhanashree Vedpathak; Srinivas Mummidi; George I. Henderson; Lenin Mahimainathan

doi:10.1371/journal.pone.0098080

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Peer-reviewed

Research Article

Ethanol-Induced Transcriptional Activation of Programmed Cell Death 4 (Pdcd4) Is Mediated by GSK-3β Signaling in Rat Cortical Neuroblasts

Amanjot Kaur Riar,

Affiliation Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America
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Madhusudhanan Narasimhan,

Affiliations Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America, South Plains Alcohol and Addiction Research Center, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America
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Mary Latha Rathinam,

Affiliation Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America
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Dhanashree Vedpathak,

Affiliation Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America
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Srinivas Mummidi,

Affiliation Center for Personalized Medicine, South Texas Veterans Health Care System, and University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
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George I. Henderson,

Affiliations Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America, South Plains Alcohol and Addiction Research Center, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America
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Lenin Mahimainathan

* E-mail: lenin.mahimainathan@ttuhsc.edu

Affiliations Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America, South Plains Alcohol and Addiction Research Center, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America
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Ethanol-Induced Transcriptional Activation of Programmed Cell Death 4 (Pdcd4) Is Mediated by GSK-3β Signaling in Rat Cortical Neuroblasts

Amanjot Kaur Riar,
Madhusudhanan Narasimhan,
Mary Latha Rathinam,
Dhanashree Vedpathak,
Srinivas Mummidi,
George I. Henderson,
Lenin Mahimainathan

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Published: May 16, 2014
https://doi.org/10.1371/journal.pone.0098080

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Neuroblasts
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Ethanol
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Messenger RNA
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Phosphorylation
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Transfection
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Neuronal differentiation
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Small interfering RNA
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Transcriptional control
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