Oocytes with a Dark Zona Pellucida Demonstrate Lower Fertilization, Implantation and Clinical Pregnancy Rates in IVF/ICSI Cycles

Wei Shi; Bo Xu; Li-Min Wu; Ren-Tao Jin; Hong-Bing Luan; Li-Hua Luo; Qing Zhu; Lars Johansson; Yu-Sheng Liu; Xian-Hong Tong

doi:10.1371/journal.pone.0089409

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Peer-reviewed

Research Article

Oocytes with a Dark Zona Pellucida Demonstrate Lower Fertilization, Implantation and Clinical Pregnancy Rates in IVF/ICSI Cycles

Wei Shi ,

Contributed equally to this work with: Wei Shi, Bo Xu

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Bo Xu ,

Contributed equally to this work with: Wei Shi, Bo Xu

* E-mail: bio_xubo@163.com (BX); shengzhizhongxin@126.com (YSL); tong68xianhong@163.com (XHT)

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Li-Min Wu,

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Ren-Tao Jin,

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Hong-Bing Luan,

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Li-Hua Luo,

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Qing Zhu,

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Lars Johansson,

Affiliation Centre for Assisted Reproduction, Codra Hospital, Podgorica, Montenegro
⨯
Yu-Sheng Liu ,

* E-mail: bio_xubo@163.com (BX); shengzhizhongxin@126.com (YSL); tong68xianhong@163.com (XHT)

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯
Xian-Hong Tong

* E-mail: bio_xubo@163.com (BX); shengzhizhongxin@126.com (YSL); tong68xianhong@163.com (XHT)

Affiliation Center for Reproductive Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, China
⨯

Oocytes with a Dark Zona Pellucida Demonstrate Lower Fertilization, Implantation and Clinical Pregnancy Rates in IVF/ICSI Cycles

Wei Shi,
Bo Xu,
Li-Min Wu,
Ren-Tao Jin,
Hong-Bing Luan,
Li-Hua Luo,
Qing Zhu,
Lars Johansson,
Yu-Sheng Liu,
Xian-Hong Tong

x

Published: February 24, 2014
https://doi.org/10.1371/journal.pone.0089409

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Oocytes
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Mitochondria
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Embryos
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Fertilization
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Medical implants
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Zona pellucida
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