Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data

• Jonathan D. Mosley,

  Affiliation Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Sara L. Van Driest,

  Affiliation Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, United States of America

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• Emma K. Larkin,

  Affiliation Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Peter E. Weeke,

  Affiliation Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• John S. Witte,

  Affiliation Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America

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• Quinn S. Wells,

  Affiliation Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Jason H. Karnes,

  Affiliation Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Yan Guo,

  Affiliation Department of Cancer Biology, Vanderbilt University, Nashville, Tennessee, United States of America

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• Lisa Bastarache,

  Affiliation Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, United States of America

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• Lana M. Olson,

  Affiliation Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America

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• Catherine A. McCarty,

  Affiliation Essentia Institute of Rural Health, Duluth, Minnesota, United States of America

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• Jennifer A. Pacheco,

  Affiliation Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

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• Gail P. Jarvik,

  Affiliation Departments of Medicine (Medical Genetics) and Genome Sciences, University of Washington, Seattle, Washington, United States of America

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• David S. Carrell,

  Affiliation Group Health Research Institute, Seattle, Washington, United States of America

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• Eric B. Larson,

  Affiliation Group Health Research Institute, Seattle, Washington, United States of America

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• David R. Crosslin,

  Affiliation Departments of Medicine (Medical Genetics) and Genome Sciences, University of Washington, Seattle, Washington, United States of America

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• Iftikhar J. Kullo,

  Affiliation Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

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• Gerard Tromp,

  Affiliation The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania, United States of America

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• Helena Kuivaniemi,

  Affiliation The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania, United States of America

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• David J. Carey,

  Affiliation The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania, United States of America

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• Marylyn D. Ritchie,

  Affiliation Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United States of America

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• Josh C. Denny,

  Affiliations Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America, Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, United States of America

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•  [ ... ],
• Dan M. Roden

  * E-mail: dan.roden@vanderbilt.edu

  Affiliation Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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