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Open Access

Peer-reviewed

Research Article

Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System

  • Woong Y. Hwang ,

    Contributed equally to this work with: Woong Y. Hwang, Yanfang Fu

    Affiliations Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

    ⨯
  • Yanfang Fu ,

    Contributed equally to this work with: Woong Y. Hwang, Yanfang Fu

    Affiliations Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    ⨯
  • Deepak Reyon,

    Affiliations Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    ⨯
  • Morgan L. Maeder,

    Affiliation Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

    ⨯
  • Prakriti Kaini,

    Affiliations Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

    ⨯
  • Jeffry D. Sander,

    Affiliations Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    ⨯
  • J. Keith Joung,

    Affiliations Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

    ⨯
  • Randall T. Peterson ,

    jyeh1@partners.org (JY); peterson@cvrc.mgh.harvard.edu (RTP)

    Affiliations Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America

    ⨯
  • Jing-Ruey Joanna Yeh

    jyeh1@partners.org (JY); peterson@cvrc.mgh.harvard.edu (RTP)

    Affiliations Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

    ⨯

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