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Open Access

Peer-reviewed

Research Article

Peripheral Reduction of FGFR4 with Antisense Oligonucleotides Increases Metabolic Rate and Lowers Adiposity in Diet-Induced Obese Mice

  • Xing Xian Yu ,

    xyu@isisph.com

    Affiliation Department of Antisense Drug Discovery, Isis Pharmaceuticals Inc., Carlsbad, California, United States of America

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  • Lynnetta M. Watts,

    Affiliation Department of Clinical Development, Isis Pharmaceuticals Inc., Carlsbad, California, United States of America

    ⨯
  • Vara Prasad Manchem,

    Affiliation Department of Antisense Drug Discovery, Isis Pharmaceuticals Inc., Carlsbad, California, United States of America

    ⨯
  • Kaushik Chakravarty,

    Affiliation Department of Antisense Drug Discovery, Isis Pharmaceuticals Inc., Carlsbad, California, United States of America

    ⨯
  • Brett P. Monia,

    Affiliation Department of Antisense Drug Discovery, Isis Pharmaceuticals Inc., Carlsbad, California, United States of America

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  • Michael L. McCaleb,

    Affiliation Department of Antisense Drug Discovery, Isis Pharmaceuticals Inc., Carlsbad, California, United States of America

    ⨯
  • Sanjay Bhanot

    Affiliation Department of Clinical Development, Isis Pharmaceuticals Inc., Carlsbad, California, United States of America

    ⨯

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