Patterns of Risk of Cancer in Patients with Metal-on-Metal Hip Replacements versus Other Bearing Surface Types: A Record Linkage Study between a Prospective Joint Registry and General Practice Electronic Health Records in England

• Arief Lalmohamed,

  Affiliations Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands, Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands

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• Alexander J. MacGregor,

  Affiliation Norwich Medical School, University of East Anglia, Norwich United Kingdom

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• Frank de Vries,

  Affiliations Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands, Medical Research Council (MRC) Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, United Kingdom, Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Centre+, Maastricht, The Netherlands, Care and Public Health Research Institute (CAPHRI), Maastricht, The Netherlands

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• Hubertus G. M. Leufkens,

  Affiliation Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands

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• Tjeerd P. van Staa

  * E-mail: tjeerd.vanstaa@mhra.gsi.gov.uk

  Affiliations Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands, Medical Research Council (MRC) Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, United Kingdom, Clinical Practice Research Datalink (CPRD), Medicines and Healthcare products Regulatory Agency, London, United Kingdom

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