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Open Access

Peer-reviewed

Research Article

HMGB1 Accelerates Alveolar Epithelial Repair via an IL-1β- and αvβ6 Integrin-dependent Activation of TGF-β1

  • Jean-François Pittet ,

    Contributed equally to this work with: Jean-François Pittet, Hidefumi Koh

    Affiliation Departments of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Hidefumi Koh ,

    Contributed equally to this work with: Jean-François Pittet, Hidefumi Koh

    Affiliation Division of Pulmonary Medicine, Keio University School of Medicine, Tokyo, Japan

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  • Xiaohui Fang,

    Affiliation Department of Medicine and Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America

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  • Karen Iles,

    Affiliations Departments of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Environmental Health Sciences, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Sarah Christiaans,

    Affiliation Departments of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Naseem Anjun,

    Affiliation Departments of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Brant M. Wagener,

    Affiliation Departments of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Dae Won Park,

    Affiliations Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Division of Infectious Diseases, Korea University Ansan Hospital, Ansan, Republic of Korea

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  • Jaroslaw W. Zmijewski,

    Affiliation Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Michael A. Matthay,

    Affiliation Department of Medicine and Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America

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  • Jérémie Roux

    Jeremie_Roux@hms.harvard.edu

    Affiliation Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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