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Identification of Multiple Novel Protein Biomarkers Shed by Human Serous Ovarian Tumors into the Blood of Immunocompromised Mice and Verified in Patient Sera

  • Lynn A. Beer,

    Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

  • Huan Wang,

    Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

  • Hsin-Yao Tang,

    Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

  • Zhijun Cao,

    Current address: The National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arizona, United States of America

    Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

  • Tony Chang-Wong,

    Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

  • Janos L. Tanyi,

    Affiliation Ovarian Cancer Research Center, The University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  • Rugang Zhang,

    Affiliation Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

  • Qin Liu,

    Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

  • David W. Speicher

    speicher@wistar.org

    Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

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