A Series of Beta-Carboline Derivatives Inhibit the Kinase Activity of PLKs

Xiaomin Han; Jing Zhang; Liang Guo; Rihui Cao; Yongzhen Li; Ni Li; Qin Ma; Jialin Wu; Yanchang Wang; Shuyi Si

doi:10.1371/journal.pone.0046546

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Open Access

Peer-reviewed

Research Article

A Series of Beta-Carboline Derivatives Inhibit the Kinase Activity of PLKs

Xiaomin Han ,

Contributed equally to this work with: Xiaomin Han, Jing Zhang

Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
⨯
Jing Zhang ,

Contributed equally to this work with: Xiaomin Han, Jing Zhang

Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
⨯
Liang Guo,

Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
⨯
Rihui Cao,

Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
⨯
Yongzhen Li,

Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
⨯
Ni Li,

Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
⨯
Qin Ma,

Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
⨯
Jialin Wu ,

* E-mail: sisyimb@hotmail.com (SS); yanchang.wang@med.fsu.edu (YW); hsd_100@163.com (JW)

Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
⨯
Yanchang Wang ,

* E-mail: sisyimb@hotmail.com (SS); yanchang.wang@med.fsu.edu (YW); hsd_100@163.com (JW)

Affiliation Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United States of America
⨯
Shuyi Si

* E-mail: sisyimb@hotmail.com (SS); yanchang.wang@med.fsu.edu (YW); hsd_100@163.com (JW)

Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
⨯

A Series of Beta-Carboline Derivatives Inhibit the Kinase Activity of PLKs

Xiaomin Han,
Jing Zhang,
Liang Guo,
Rihui Cao,
Yongzhen Li,
Ni Li,
Qin Ma,
Jialin Wu,
Yanchang Wang,
Shuyi Si

x

Published: October 3, 2012
https://doi.org/10.1371/journal.pone.0046546

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