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Open Access

Peer-reviewed

Research Article

A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

  • Xiang Ling ,

    Contributed equally to this work with: Xiang Ling, Shousong Cao

    Affiliation Departments of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, United States of America

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  • Shousong Cao ,

    Contributed equally to this work with: Xiang Ling, Shousong Cao

    Affiliations Departments of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, United States of America, Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America

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  • Qiuying Cheng,

    Affiliation Departments of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, United States of America

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  • James T. Keefe,

    Affiliation Departments of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, United States of America

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  • Youcef M. Rustum,

    Affiliations Departments of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, United States of America, NCI-supported Experimental Therapeutics Program, Roswell Park Cancer Institute, Buffalo, New York, United States of America

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  • Fengzhi Li

    fengzhi.li@roswellpark.org

    Affiliations Departments of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, United States of America, NCI-supported Experimental Therapeutics Program, Roswell Park Cancer Institute, Buffalo, New York, United States of America

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