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Synthetic Spike-in Standards Improve Run-Specific Systematic Error Analysis for DNA and RNA Sequencing

  • Justin M. Zook ,

    zook@nist.gov

    Affiliation Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland, United States of America

  • Daniel Samarov,

    Affiliation Statistical Engineering Division, National Institute of Standards and Technology, Gaithersburg, Maryland, United States of America

  • Jennifer McDaniel,

    Affiliation Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland, United States of America

  • Shurjo K. Sen,

    Affiliation Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  • Marc Salit

    Affiliation Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland, United States of America

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