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ATP Induced Brain-Derived Neurotrophic Factor Expression and Release from Osteoarthritis Synovial Fibroblasts Is Mediated by Purinergic Receptor P2X4

  • Kerstin Klein,

    Affiliations Center of Experimental Rheumatology, Division of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland, Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland

  • André Aeschlimann,

    Affiliation RehaClinic, Bad Zurzach, Switzerland

  • Suzana Jordan,

    Affiliations Center of Experimental Rheumatology, Division of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland, Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland

  • Renate Gay,

    Affiliations Center of Experimental Rheumatology, Division of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland, Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland

  • Steffen Gay,

    Affiliations Center of Experimental Rheumatology, Division of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland, Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland

  • Haiko Sprott

    haiko.sprott@painclinic.eu

    Affiliations Center of Experimental Rheumatology, Division of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland, Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland

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