Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

• Jeremy Sokolove ,

  Contributed equally to this work with: Jeremy Sokolove, Reuven Bromberg

  * E-mail: sokolove@stanford.edu (JS); wrobins@stanford.edu (WHR)

  Affiliations Division of Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America, VA Palo Alto Health Care System, Palo Alto, California, United States of America

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• Reuven Bromberg ,

  Contributed equally to this work with: Jeremy Sokolove, Reuven Bromberg

  Affiliations Division of Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America, VA Palo Alto Health Care System, Palo Alto, California, United States of America

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• Kevin D. Deane,

  Affiliation Division of Rheumatology, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, United States of America

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• Lauren J. Lahey,

  Affiliations Division of Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America, Department of Statistics, Stanford University School of Medicine, Stanford, California, United States of America

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• Lezlie A. Derber,

  Affiliation Division of Rheumatology, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, United States of America

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• Piyanka E. Chandra,

  Affiliations Division of Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America, Department of Statistics, Stanford University School of Medicine, Stanford, California, United States of America

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• Jess D. Edison,

  Affiliation Walter Reed Army Medical Center, Washington, D.C., United States of America

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• William R. Gilliland,

  Affiliation Walter Reed Army Medical Center, Washington, D.C., United States of America

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• Robert J. Tibshirani,

  Affiliations Department of Statistics, Stanford University School of Medicine, Stanford, California, United States of America, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, United States of America

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• Jill M. Norris,

  Affiliation Department of Epidemiology, Colorado School of Public Health, University of Colorado, Aurora, Colorado, United States of America

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• V. Michael Holers,

  Affiliation Division of Rheumatology, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, United States of America

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• William H. Robinson

  * E-mail: sokolove@stanford.edu (JS); wrobins@stanford.edu (WHR)

  Affiliations Division of Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America, VA Palo Alto Health Care System, Palo Alto, California, United States of America

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