Changes in Channel Trafficking and Protein Stability Caused by LQT2 Mutations in the PAS Domain of the HERG Channel

Open Access

Peer-reviewed

Research Article

Carol A. Harley ,

* E-mail: harleyca@ibmc.up.pt

Affiliation IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
⨯
Catarina S. H. Jesus,

Affiliations Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra Portugal, Chemistry Department, Faculty of Science and Technology, University of Coimbra, Coimbra Portugal
⨯
Ricardo Carvalho,

Affiliation IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
⨯
Rui M. M. Brito,

Affiliations Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra Portugal, Chemistry Department, Faculty of Science and Technology, University of Coimbra, Coimbra Portugal
⨯
João H. Morais-Cabral

Affiliation IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
⨯

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Protein transport
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Cell cultures
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Point mutation
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Protein domains
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Melting
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Phenotypes
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Urea
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Protein structure
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