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Ashwagandha Derived Withanone Targets TPX2-Aurora A Complex: Computational and Experimental Evidence to its Anticancer Activity

  • Abhinav Grover ,

    Contributed equally to this work with: Abhinav Grover, Rumani Singh

    Affiliation Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi, India

  • Rumani Singh ,

    Contributed equally to this work with: Abhinav Grover, Rumani Singh

    Affiliations National Institute of Advanced Industrial Science & Technology (AIST), Central 4, Tsukuba, Ibaraki, Japan, Graduate School of Life & Environmental Sciences, University of Tsukuba, Ibaraki, Japan

  • Ashutosh Shandilya,

    Affiliation Supercomputing Facility for Bioinformatics and Computational Biology, Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi, India

  • Didik Priyandoko,

    Affiliations National Institute of Advanced Industrial Science & Technology (AIST), Central 4, Tsukuba, Ibaraki, Japan, Graduate School of Life & Environmental Sciences, University of Tsukuba, Ibaraki, Japan

  • Vibhuti Agrawal,

    Affiliation Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi, India

  • Virendra S. Bisaria,

    Affiliation Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi, India

  • Renu Wadhwa,

    Affiliation National Institute of Advanced Industrial Science & Technology (AIST), Central 4, Tsukuba, Ibaraki, Japan

  • Sunil C. Kaul ,

    s-kaul@aist.go.jp (SCK); sundar@dbeb.iitd.ac.in (DS)

    Affiliation National Institute of Advanced Industrial Science & Technology (AIST), Central 4, Tsukuba, Ibaraki, Japan

  • Durai Sundar

    s-kaul@aist.go.jp (SCK); sundar@dbeb.iitd.ac.in (DS)

    Affiliation Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi, India

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