Identification of Sequence Variants in Genetic Disease-Causing Genes Using Targeted Next-Generation Sequencing

Xiaoming Wei; Xiangchun Ju; Xin Yi; Qian Zhu; Ning Qu; Tengfei Liu; Yang Chen; Hui Jiang; Guanghui Yang; Ruan Zhen; Zhangzhang Lan; Ming Qi; Jinming Wang; Yi Yang; Yuxing Chu; Xiaoyan Li; Yanfang Guang; Jian Huang

doi:10.1371/journal.pone.0029500

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Open Access

Peer-reviewed

Research Article

Identification of Sequence Variants in Genetic Disease-Causing Genes Using Targeted Next-Generation Sequencing

Xiaoming Wei ,

Contributed equally to this work with: Xiaoming Wei, Xiangchun Ju, Xin Yi

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Xiangchun Ju ,

Contributed equally to this work with: Xiaoming Wei, Xiangchun Ju, Xin Yi

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Xin Yi ,

Contributed equally to this work with: Xiaoming Wei, Xiangchun Ju, Xin Yi

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Qian Zhu,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Ning Qu,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Tengfei Liu,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Yang Chen,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Hui Jiang,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Guanghui Yang,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Ruan Zhen,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Zhangzhang Lan,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Ming Qi,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Jinming Wang,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Yi Yang,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Yuxing Chu,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Xiaoyan Li,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
Yanfang Guang,

Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China
⨯
[ ... ],
Jian Huang

* E-mail: huangjchgc@hotmail.com

Affiliations Beijing Genomics Institute at Shenzhen, Shenzhen, China, Shanghai-Ministry Key Laboratory of Disease and Health Genomics, National Engineering Center for Biochip at Shanghai, Shanghai, China
⨯
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Identification of Sequence Variants in Genetic Disease-Causing Genes Using Targeted Next-Generation Sequencing

Xiaoming Wei,
Xiangchun Ju,
Xin Yi,
Qian Zhu,
Ning Qu,
Tengfei Liu,
Yang Chen,
Hui Jiang,
Guanghui Yang,
Ruan Zhen

x

Published: December 21, 2011
https://doi.org/10.1371/journal.pone.0029500

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Deletion mutation
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Mutation databases
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Heterozygosity
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Duchenne muscular dystrophy
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Next-generation sequencing
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