Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes

• Kishore Viswanathan ,

  Contributed equally to this work with: Kishore Viswanathan, Kathleen M. Frey

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, United States of America

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• Kathleen M. Frey ,

  Contributed equally to this work with: Kishore Viswanathan, Kathleen M. Frey

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, United States of America

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• Eric W. Scocchera,

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, United States of America

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• Brooke D. Martin,

  Affiliation Promiliad Biopharma Inc., Alberton, Montana, United States of America

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• P. Whitney Swain III,

  Affiliation Promiliad Biopharma Inc., Alberton, Montana, United States of America

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• Jeremy B. Alverson,

  Affiliation Promiliad Biopharma Inc., Alberton, Montana, United States of America

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• Nigel D. Priestley,

  Affiliation Promiliad Biopharma Inc., Alberton, Montana, United States of America

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• Amy C. Anderson ,

  * E-mail: amy.anderson@uconn.edu (ACA) (AA); dennis.wright@uconn.edu (DLW) (DW)

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, United States of America

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• Dennis L. Wright

  * E-mail: amy.anderson@uconn.edu (ACA) (AA); dennis.wright@uconn.edu (DLW) (DW)

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, United States of America

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