Tauroursodeoxycholic Acid (TUDCA) Protects Photoreceptors from Cell Death after Experimental Retinal Detachment

Dimosthenis Mantopoulos; Yusuke Murakami; Jason Comander; Aristomenis Thanos; Miin Roh; Joan W. Miller; Demetrios G. Vavvas

doi:10.1371/journal.pone.0024245

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Peer-reviewed

Research Article

Tauroursodeoxycholic Acid (TUDCA) Protects Photoreceptors from Cell Death after Experimental Retinal Detachment

Dimosthenis Mantopoulos,

Affiliation Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
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Yusuke Murakami,

Affiliation Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
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Jason Comander,

Affiliation Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
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Aristomenis Thanos,

Affiliation Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
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Miin Roh,

Affiliation Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
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Joan W. Miller,

Affiliation Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
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Demetrios G. Vavvas

* E-mail: vavvas@meei.harvard.edu

Affiliation Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Tauroursodeoxycholic Acid (TUDCA) Protects Photoreceptors from Cell Death after Experimental Retinal Detachment

Dimosthenis Mantopoulos,
Yusuke Murakami,
Jason Comander,
Aristomenis Thanos,
Miin Roh,
Joan W. Miller,
Demetrios G. Vavvas

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Published: September 22, 2011
https://doi.org/10.1371/journal.pone.0024245

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Retinal detachment
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Photoreceptors
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Retina
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Endoplasmic reticulum
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Apoptosis
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Neuroprotectives
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Inflammation
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Vision
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