Promoter Methylation in Head and Neck Squamous Cell Carcinoma Cell Lines Is Significantly Different than Methylation in Primary Tumors and Xenografts

• Patrick T. Hennessey,

  Affiliation Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

  ⨯
• Michael F. Ochs,

  Affiliations Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Division of Biostatistics and Bioinformatics, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

  ⨯
• Wojciech W. Mydlarz,

  Affiliation Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

  ⨯
• Wayne Hsueh,

  Affiliation Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  ⨯
• Leslie Cope,

  Affiliations Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Division of Biostatistics and Bioinformatics, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

  ⨯
• Wayne Yu,

  Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

  ⨯
• Joseph A. Califano

  * E-mail: jcalifa@jhmi.edu

  Affiliations Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Milton J. Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland, United States of America

  ⨯