Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2

• David Ramonet ,

  Contributed equally to this work with: David Ramonet, João Paulo L. Daher

  Affiliation Brain Mind Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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• João Paulo L. Daher ,

  Contributed equally to this work with: David Ramonet, João Paulo L. Daher

  Affiliations NeuroRegeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Pathology, School of Medicine, Fluminense Federal University, Niterói, Brazil

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• Brian M. Lin,

  Affiliations NeuroRegeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Klodjan Stafa,

  Affiliation Brain Mind Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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• Jaekwang Kim,

  Affiliations Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Institute for Translational Neuroscience, Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Rebecca Banerjee,

  Affiliation Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York, United States of America

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• Marie Westerlund,

  Affiliation Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

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• Olga Pletnikova,

  Affiliation Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Liliane Glauser,

  Affiliation Brain Mind Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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• Lichuan Yang,

  Affiliation Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York, United States of America

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• Ying Liu,

  Affiliation Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Deborah A. Swing,

  Affiliation Mouse Cancer Genetics Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland, United States of America

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• M. Flint Beal,

  Affiliation Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York, United States of America

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• Juan C. Troncoso,

  Affiliation Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• J. Michael McCaffery,

  Affiliation Integrated Imaging Center and Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Nancy A. Jenkins,

  Current address: Institute of Molecular and Cell Biology, Singapore, Singapore

  Affiliation Mouse Cancer Genetics Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland, United States of America

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• Neal G. Copeland,

  Current address: Institute of Molecular and Cell Biology, Singapore, Singapore

  Affiliation Mouse Cancer Genetics Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland, United States of America

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• Dagmar Galter,

  Affiliation Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

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• Bobby Thomas,

  Affiliation Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York, United States of America

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• Michael K. Lee,

  Affiliations Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Institute for Translational Neuroscience, Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Ted M. Dawson,

  Affiliations NeuroRegeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Valina L. Dawson ,

  * E-mail: darren.moore@epfl.ch (DJM); vdawson@jhmi.edu (VLD)

  Affiliations NeuroRegeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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•  [ ... ],
• Darren J. Moore

  * E-mail: darren.moore@epfl.ch (DJM); vdawson@jhmi.edu (VLD)

  Affiliation Brain Mind Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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