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Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis

  • Fei Zhu,

    Affiliation Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America

  • Pu Wang,

    Affiliation Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America

  • Norman H. Lee,

    Affiliation Department of Pharmacology and Physiology, The George Washington University Medical Center, Washington, D.C., United States of America

  • Mary B. Goldring,

    Affiliation Hospital for Special Surgery, New York, New York, United States of America

  • Konstantinos Konstantopoulos

    kkonsta1@jhu.edu

    Affiliations Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America, Johns Hopkins Physical Sciences in Oncology Center and Institute for NanoBioTechnology, The Johns Hopkins University, Baltimore, Maryland, United States of America

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