Amyloid-Like Aggregates of the Yeast Prion Protein Ure2 Enter Vertebrate Cells by Specific Endocytotic Pathways and Induce Apoptosis

• Chen Zhang,

  Affiliations National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Graduate University of the Chinese Academy of Sciences, Beijing, China

  ⨯
• Antony P. Jackson,

  Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Zai-Rong Zhang,

  Affiliations National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Graduate University of the Chinese Academy of Sciences, Beijing, China

  ⨯
• Yan Han,

  Affiliation Department of Neurobiology and the Sino-Japan Joint Laboratory of Neurodegenerative Diseases, Beijing Institute of Geriatrics, Xuanwu Hospital of the Capital University of Medical Sciences, Beijing, China

  ⨯
• Shun Yu,

  Affiliation Department of Neurobiology and the Sino-Japan Joint Laboratory of Neurodegenerative Diseases, Beijing Institute of Geriatrics, Xuanwu Hospital of the Capital University of Medical Sciences, Beijing, China

  ⨯
• Rong-Qiao He,

  Affiliation State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

  ⨯
• Sarah Perrett

  * E-mail: sarah.perrett@cantab.net

  Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

  ⨯