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Open Access

Peer-reviewed

Research Article

JAK2 V617F Constitutive Activation Requires JH2 Residue F595: A Pseudokinase Domain Target for Specific Inhibitors

  • Alexandra Dusa,

    Affiliations Ludwig Institute for Cancer Research Ltd., Brussels, Belgium, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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  • Céline Mouton,

    Affiliations Ludwig Institute for Cancer Research Ltd., Brussels, Belgium, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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  • Christian Pecquet,

    Affiliations Ludwig Institute for Cancer Research Ltd., Brussels, Belgium, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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  • Murielle Herman,

    Affiliations Ludwig Institute for Cancer Research Ltd., Brussels, Belgium, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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  • Stefan N. Constantinescu

    Stefan.Constantinescu@bru.licr.org

    Affiliations Ludwig Institute for Cancer Research Ltd., Brussels, Belgium, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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