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Open Access

Peer-reviewed

Research Article

Characterization of Age-Dependent and Progressive Cortical Neuronal Degeneration in Presenilin Conditional Mutant Mice

  • Mary Wines-Samuelson,

    Affiliation Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Eva C. Schulte,

    Affiliation Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Miriam J. Smith,

    Affiliation Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Chiye Aoki,

    Affiliation Center for Neural Science, New York University, New York, New York, United States of America

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  • Xinran Liu,

    Affiliation Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Raymond J. Kelleher III,

    Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Jie Shen

    jshen@rics.bwh.harvard.edu

    Affiliation Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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