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Open Access

Peer-reviewed

Research Article

How to Turn a Genetic Circuit into a Synthetic Tunable Oscillator, or a Bistable Switch

  • Lucia Marucci,

    Affiliations Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, Department of Computer and Systems Engineering, Federico II University, Naples, Italy

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  • David A. W. Barton,

    Affiliation Bristol Centre for Applied Nonlinear Mathematics, University of Bristol, Bristol, United Kingdom

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  • Irene Cantone,

    Affiliation MRC Clinical Sciences Centre Faculty of Medicine, Imperial College London, London, United Kingdom

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  • Maria Aurelia Ricci,

    Affiliation Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

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  • Maria Pia Cosma,

    Affiliation Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

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  • Stefania Santini,

    Affiliation Department of Computer and Systems Engineering, Federico II University, Naples, Italy

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  • Diego di Bernardo ,

    Contributed equally to this work with: Diego di Bernardo, Mario di Bernardo

    dibernardo@tigem.it (DDB); mario.dibernardo@unina.it (MDB)

    Affiliations Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, Department of Computer and Systems Engineering, Federico II University, Naples, Italy

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  • Mario di Bernardo

    Contributed equally to this work with: Diego di Bernardo, Mario di Bernardo

    dibernardo@tigem.it (DDB); mario.dibernardo@unina.it (MDB)

    Affiliations Department of Computer and Systems Engineering, Federico II University, Naples, Italy, Bristol Centre for Applied Nonlinear Mathematics, University of Bristol, Bristol, United Kingdom

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