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Open Access

Peer-reviewed

Research Article

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

  • Régine P. Steegers-Theunissen ,

    r.steegers@erasmusmc.nl

    Affiliations Obstetrics and Gynecology/Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands, Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands, Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands, Pediatrics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

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  • Sylvia A. Obermann-Borst,

    Affiliation Obstetrics and Gynecology/Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

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  • Dennis Kremer,

    Affiliation Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Jan Lindemans,

    Affiliation Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

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  • Cissy Siebel,

    Affiliation Child Health Care Center CAREYN, Rotterdam, Netherlands

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  • Eric A. Steegers,

    Affiliation Obstetrics and Gynecology/Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

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  • P. Eline Slagboom,

    Affiliation Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Bastiaan T. Heijmans

    Affiliation Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands

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