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Open Access

Peer-reviewed

Research Article

Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment

  • Lauren K. Dunn,

    Affiliations Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • Khalid S. Mohammad,

    Affiliation Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • Pierrick G. J. Fournier,

    Affiliation Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • C. Ryan McKenna,

    Affiliation Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • Holly W. Davis,

    Affiliation Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • Maria Niewolna,

    Affiliation Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • Xiang Hong Peng,

    Affiliation Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • John M. Chirgwin,

    Affiliations Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯
  • Theresa A. Guise

    tguise@iupui.edu

    Affiliation Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

    ⨯

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