Clofazimine Inhibits Human Kv1.3 Potassium Channel by Perturbing Calcium Oscillation in T Lymphocytes

• Yunzhao R. Ren,

  Affiliations Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Program in Biochemistry, Cellular and Molecular Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Fan Pan,

  Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Suhel Parvez,

  Affiliation Center for Biomedical Research at The Queen's Medical Center and John A. Burns School of Medicine at the University of Hawaii, Honolulu, Hawaii, United States of America

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• Andrea Fleig,

  Affiliation Center for Biomedical Research at The Queen's Medical Center and John A. Burns School of Medicine at the University of Hawaii, Honolulu, Hawaii, United States of America

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• Curtis R. Chong,

  Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Jing Xu,

  Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Yongjun Dang,

  Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Jin Zhang,

  Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Hongsi Jiang,

  Affiliation Department of Medicine, Feinberg School of Medicine, Northwestern University, Evanston, Illinois, United States of America

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• Reinhold Penner,

  Affiliation Center for Biomedical Research at The Queen's Medical Center and John A. Burns School of Medicine at the University of Hawaii, Honolulu, Hawaii, United States of America

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• Jun O. Liu

  * E-mail: joliu@jhu.edu

  Affiliations Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Program in Biochemistry, Cellular and Molecular Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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