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Open Access

Peer-reviewed

Research Article

Nicotine Acts on Growth Plate Chondrocytes to Delay Skeletal Growth through the α7 Neuronal Nicotinic Acetylcholine Receptor

  • Atsuo Kawakita,

    Affiliations Department of Reproductive Biology, National Institute for Child Health and Development, Tokyo, Japan, Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan

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  • Kazuki Sato,

    Affiliation Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan

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  • Hatsune Makino,

    Affiliation Department of Reproductive Biology, National Institute for Child Health and Development, Tokyo, Japan

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  • Hiroyasu Ikegami,

    Affiliation Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan

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  • Shinichiro Takayama,

    Affiliation Department of Orthopaedic Surgery, National Center for Child Health and Development, Tokyo, Japan

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  • Yoshiaki Toyama,

    Affiliation Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan

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  • Akihiro Umezawa

    umezawa@1985.jukuin.keio.ac.jp

    Affiliation Department of Reproductive Biology, National Institute for Child Health and Development, Tokyo, Japan

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