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Open Access

Peer-reviewed

Research Article

Targeted Chromosomal Insertion of Large DNA into the Human Genome by a Fiber-Modified High-Capacity Adenovirus-Based Vector System

  • Manuel A. F. V. Gonçalves ,

    m.goncalves@lumc.nl

    Affiliation Virus and Stem Cell Biology Laboratory, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

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  • Maarten Holkers,

    Affiliation Virus and Stem Cell Biology Laboratory, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

    ⨯
  • Gijsbert P. van Nierop,

    Affiliation Virus and Stem Cell Biology Laboratory, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

    ⨯
  • Roeland Wieringa,

    Affiliation Virus and Stem Cell Biology Laboratory, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

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  • Maria G. Pau,

    Affiliation Crucell Holland BV, Leiden, The Netherlands

    ⨯
  • Antoine A. F. de Vries

    Affiliation Virus and Stem Cell Biology Laboratory, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

    ⨯

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