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Research Article

Cellular Islet Autoimmunity Associates with Clinical Outcome of Islet Cell Transplantation

  • Volkert A. L. Huurman equal contributor,

    equal contributor Contributed equally to this work with: Volkert A. L. Huurman, Robert Hilbrands

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Robert Hilbrands equal contributor,

    equal contributor Contributed equally to this work with: Volkert A. L. Huurman, Robert Hilbrands

    Affiliations: Diabetes Research Center, Brussels Free University-VUB, Brussels, Belgium, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Gabriëlle G. M. Pinkse,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Pieter Gillard,

    Affiliations: Diabetes Research Center, Brussels Free University-VUB, Brussels, Belgium, Laboratory for Experimental Medicine & Endocrinology (LEGENDO), University Hospital Gasthuisberg, Catholic University of Leuven-KUL, Leuven, Belgium, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Gaby Duinkerken,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Pieter van de Linde,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Petronella M. W. van der Meer-Prins,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Minke F. J. Versteeg-van der Voort Maarschalk,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Koen Verbeeck,

    Affiliations: Diabetes Research Center, Brussels Free University-VUB, Brussels, Belgium, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Behrooz Z. Alizadeh,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Chantal Mathieu,

    Affiliations: Laboratory for Experimental Medicine & Endocrinology (LEGENDO), University Hospital Gasthuisberg, Catholic University of Leuven-KUL, Leuven, Belgium, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Frans K. Gorus,

    Affiliations: Diabetes Research Center, Brussels Free University-VUB, Brussels, Belgium, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Dave L. Roelen,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Frans H. J. Claas,

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Bart Keymeulen,

    Affiliations: Diabetes Research Center, Brussels Free University-VUB, Brussels, Belgium, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Daniel G. Pipeleers,

    Affiliations: Diabetes Research Center, Brussels Free University-VUB, Brussels, Belgium, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Bart O. Roep mail

    boroep@lumc.nl

    Affiliations: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands, JDRF Center for Beta Cell Therapy in Diabetes, Brussels, Belgium

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  • Published: June 18, 2008
  • DOI: 10.1371/journal.pone.0002435

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