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Enhancement of Allele Discrimination by Introduction of Nucleotide Mismatches into siRNA in Allele-Specific Gene Silencing by RNAi

  • Yusuke Ohnishi,

    Affiliations Department of Molecular Genetics, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan, Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

  • Yoshiko Tamura,

    Affiliation Department of Molecular Genetics, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan

  • Mariko Yoshida,

    Affiliation Department of Molecular Genetics, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan

  • Katsushi Tokunaga,

    Affiliation Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

  • Hirohiko Hohjoh

    hohjohh@ncnp.go.jp

    Affiliation Department of Molecular Genetics, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan

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