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Probiotic Escherichia coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity

  • Sya N. Ukena ,

    To whom correspondence should be addressed. E-mail: Florian.Gunzer@tu-dresden.de

    Affiliations Department of Mucosal Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany, Department of Haematology, Haemostaseology and Oncology, Hannover Medical School, Hannover, Germany

  • Anurag Singh,

    Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

  • Ulrike Dringenberg,

    Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

  • Regina Engelhardt,

    Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

  • Ursula Seidler,

    Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

  • Wiebke Hansen,

    Affiliation Department of Mucosal Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany

  • André Bleich,

    Affiliation Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, Hannover, Germany

  • Dunja Bruder,

    Affiliation Immune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany

  • Anke Franzke,

    Affiliation Department of Haematology, Haemostaseology and Oncology, Hannover Medical School, Hannover, Germany

  • Gerhard Rogler,

    Affiliation Department of Internal Medicine, Gastroenterological and Hepatology Unit, University Hospital of Zurich, Zurich, Switzerland

  • Sebastian Suerbaum,

    Affiliation Department of Haematology, Haemostaseology and Oncology, Hannover Medical School, Hannover, Germany

  • Jan Buer,

    Affiliation Institute of Medical Microbiology, University Hospital Essen, Essen, Germany

  • Florian Gunzer,

    Affiliation Faculty of Medicine Carl Gustav Carus, Institute for Medical Microbiology and Hygiene, Technology University (TU) Dresden, Dresden, Germany

  • Astrid M. Westendorf

    Affiliation Department of Mucosal Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany

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