Persistent Release of IL-1s from Skin Is Associated with Systemic Cardio-Vascular Disease, Emaciation and Systemic Amyloidosis: The Potential of Anti-IL-1 Therapy for Systemic Inflammatory Diseases

• Keiichi Yamanaka ,

  * E-mail: yamake@clin.medic.mie-u.ac.jp

  Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Takehisa Nakanishi,

  Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Hiromitsu Saito,

  Affiliation Department of Animal Genomics, Functional Genomics Institute, Mie University Life Science Research Center, Tsu, Mie, Japan

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• Junko Maruyama,

  Affiliation Department of Clinical Engineering, Suzuka University of Medical Science, Suzuka, Mie, Japan

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• Kenichi Isoda,

  Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Ayumu Yokochi,

  Affiliation Anesthesiology and Critical Care Medicine, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Kyoko Imanaka-Yoshida,

  Affiliations Pathology and Matrix Biology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan, Mie University Research Center for Matrix Biology, Tsu, Mie, Japan

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• Kenshiro Tsuda,

  Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Masato Kakeda,

  Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Ryuji Okamoto,

  Affiliation Cardiology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Satoshi Fujita,

  Affiliation Cardiology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Yoichiro Iwakura,

  Affiliation Division of Experimental Animal Immunology, Tokyo University of Science, Noda, Chiba, Japan

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• Noboru Suzuki,

  Affiliation Department of Animal Genomics, Functional Genomics Institute, Mie University Life Science Research Center, Tsu, Mie, Japan

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• Masaaki Ito,

  Affiliation Cardiology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Kazuo Maruyama,

  Affiliation Anesthesiology and Critical Care Medicine, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Esteban C. Gabazza,

  Affiliation Immunology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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• Toshimichi Yoshida,

  Affiliations Pathology and Matrix Biology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan, Mie University Research Center for Matrix Biology, Tsu, Mie, Japan

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• Motomu Shimaoka,

  Affiliation Molecular Pathology and Cell Adhesion Biology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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•  [ ... ],
• Hitoshi Mizutani

  Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan

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