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Research Article

Beneficial Effect of Insulin Treatment on Islet Transplantation Outcomes in Akita Mice

  • Kazuhide Kikawa,

    Affiliations: Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan, Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, Chuo-ku, Kumamoto, Japan

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  • Daisuke Sakano,

    Affiliation: Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, Chuo-ku, Kumamoto, Japan

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  • Nobuaki Shiraki,

    Affiliation: Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, Chuo-ku, Kumamoto, Japan

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  • Tomonori Tsuyama,

    Affiliation: Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, Chuo-ku, Kumamoto, Japan

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  • Kazuhiko Kume,

    Affiliation: Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, Chuo-ku, Kumamoto, Japan

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  • Fumio Endo,

    Affiliation: Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan

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  • Shoen Kume mail

    skume@kumamoto-u.ac.jp

    Affiliations: Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University, Chuo-ku, Kumamoto, Japan, Program for Leading Graduate Schools “HIGO (Health life science; Interdisciplinary and Glocal Oriented) Program,” Kumamoto University, Chuo-ku, Kumamoto, Japan

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  • Published: April 17, 2014
  • DOI: 10.1371/journal.pone.0095451

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