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Prediction and Experimental Characterization of nsSNPs Altering Human PDZ-Binding Motifs

  • David Gfeller,

    Affiliations The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Swiss Institute of Bioinformatics, Quartier Sorge, Bâtiment Génopode, Lausanne, Switzerland

  • Andreas Ernst,

    Current address: Institute of Biochemistry II, Theodor-Stern-Kai 7, Goethe-University of Frankfurt, Frankfurt, Germany

    Affiliation The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

  • Nick Jarvik,

    Affiliation The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

  • Sachdev S. Sidhu,

    Affiliations The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

  • Gary D. Bader

    gary.bader@utoronto.ca

    Affiliations The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science, University of Toronto, Toronto, Ontario, Canada

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