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Research Article

Multiple White Matter Volume Reductions in Patients with Panic Disorder: Relationships between Orbitofrontal Gyrus Volume and Symptom Severity and Social Dysfunction

  • Jun Konishi,

    Affiliation: Department of Psychiatry, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Takeshi Asami,

    Affiliation: Department of Psychiatry, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Fumi Hayano,

    Affiliation: Department of Psychiatry, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Asuka Yoshimi,

    Affiliation: Department of Psychiatry, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Shunsuke Hayasaka,

    Affiliation: Department of Psychiatry, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Hiroshi Fukushima,

    Affiliation: Department of Psychiatry, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Thomas J. Whitford,

    Affiliation: School of Psychology, University of New South Wales, Sydney, New South Wales, Australia

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  • Tomio Inoue,

    Affiliation: Department of Radiology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Yoshio Hirayasu mail

    hirayasu@yokohama-cu.ac.jp

    Affiliation: Department of Psychiatry, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

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  • Published: March 24, 2014
  • DOI: 10.1371/journal.pone.0092862

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