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Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study

  • Akkelies E. Dijkstra,

    Affiliations University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands

  • Joanna Smolonska,

    Affiliations University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands

  • Maarten van den Berge,

    Affiliations University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands

  • Ciska Wijmenga,

    Affiliation University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands

  • Pieter Zanen,

    Affiliation University of Utrecht, University Medical Center Utrecht, Department of Pulmonology, Utrecht, the Netherlands

  • Marjan A. Luinge,

    Affiliation University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, the Netherlands

  • Mathieu Platteel,

    Affiliation University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands

  • Jan-Willem Lammers,

    Affiliation University of Utrecht, University Medical Center Utrecht, Department of Pulmonology, Utrecht, the Netherlands

  • Magnus Dahlback,

    Affiliation AstraZeneca, R&D Mölndal, Mölndal, Sweden

  • Kerrie Tosh,

    Affiliation AstraZeneca, Alderley Park, Macclesfield, Cheshire, United Kingdom

  • Pieter S. Hiemstra,

    Affiliation Department of Pulmonology, Leiden University Medical Center, Leiden, the Netherlands

  • Peter J. Sterk,

    Affiliation Department of Respiratory Medicine, University of Amsterdam, Amsterdam, the Netherlands

  • Avi Spira,

    Affiliation Department of Medicine, Section of Computational Biomedicine, Boston University Medical Center, Boston, Massachusetts, United States of America

  • Jorgen Vestbo,

    Affiliations Odense University Hospital, Department of Respiratory Medicine J, and University of Southern Denmark, Clinical Institute, Odense, Denmark, Respiratory and Allergy Research Group, Manchester Academic Health Sciences Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, United Kingdom

  • Borge G. Nordestgaard,

    Affiliations The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

  • Marianne Benn,

    Affiliation Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

  • Sune F. Nielsen,

    Affiliation The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

  • Morten Dahl,

    Affiliation Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

  • W. Monique Verschuren,

    Affiliation Center for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, the Netherlands

  • H. Susan J. Picavet,

    Affiliation Center for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, the Netherlands

  • Henriette A. Smit,

    Affiliation Julius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht, the Netherlands

  • Michael Owsijewitsch,

    Affiliations Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany, Translational Lung Research Center (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany

  • Hans U. Kauczor,

    Affiliations Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany, Translational Lung Research Center (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany

  • Harry J. de Koning,

    Affiliation Department of Public Health, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands

  • Eva Nizankowska-Mogilnicka,

    Affiliation Department of Respiratory Diseases, Jagiellonian University Medical College, Krakow, Poland

  • Filip Mejza,

    Affiliation Department of Respiratory Diseases, Jagiellonian University Medical College, Krakow, Poland

  • Pawel Nastalek,

    Affiliation Department of Respiratory Diseases, Jagiellonian University Medical College, Krakow, Poland

  • Cleo C. van Diemen,

    Affiliation University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands

  • Michael H. Cho,

    Affiliations Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  • Edwin K. Silverman,

    Affiliations Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  • James D. Crapo,

    Affiliation Division of Pulmonary and Critical Care Medicine, National Jewish Health, Denver, Colorado, United States of America

  • Terri H. Beaty,

    Affiliation Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  • David A. Lomas,

    Affiliation Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

  • Per Bakke,

    Affiliation Department of Thoracic Medicine, Haukeland University, Hospital and Institute of Medicine, University of Bergen, Bergen, Norway

  • Amund Gulsvik,

    Affiliation Department of Thoracic Medicine, Haukeland University, Hospital and Institute of Medicine, University of Bergen, Bergen, Norway

  • Yohan Bossé,

    Affiliation Institut universitaire de cardiologie et de pneumologie de Québec, Department of Molecular Medicine, Laval University, Québec City, Canada

  • M. A. Obeidat,

    Affiliation Division of Respirology, Department of Medicine, James Hogg Research Centre, St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada

  • Daan W. Loth,

    Affiliations Dept Epidemiology, Erasmus MC, Rotterdam, the Netherlands, The Netherlands Healthcare Inspectorate, The Hague, the Netherlands

  • Lies Lahousse,

    Affiliations Dept Epidemiology, Erasmus MC, Rotterdam, the Netherlands, Department of respiratory medicine, University Hospital Ghent, Ghent, Belgium

  • Fernando Rivadeneira,

    Affiliations Department of Internal medicine, Erasmus MC, Rotterdam, the Netherlands, Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands

  • Andre G. Uitterlinden,

    Affiliations Department of Internal medicine, Erasmus MC, Rotterdam, the Netherlands, Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands

  • Andre Hofman,

    Affiliations Dept Epidemiology, Erasmus MC, Rotterdam, the Netherlands, Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands

  • Bruno H. Stricker,

    Affiliations Dept Epidemiology, Erasmus MC, Rotterdam, the Netherlands, The Netherlands Healthcare Inspectorate, The Hague, the Netherlands

  • Guy G. Brusselle,

    Affiliations Dept Epidemiology, Erasmus MC, Rotterdam, the Netherlands, Department of respiratory medicine, University Hospital Ghent, Ghent, Belgium

  • Cornelia M. van Duijn,

    Affiliation Genetic Epidemiology Unit, Department of Epidemiology, Erasmus Medical Center, University Medical Center, Rotterdam, the Netherlands

  • Uilke Brouwer,

    Affiliations University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, the Netherlands

  • Gerard H. Koppelman,

    Affiliations University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, Beatrix Childrens' Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, the Netherlands

  • Judith M. Vonk,

    Affiliations University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands

  • Martijn C. Nawijn,

    Affiliations University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, the Netherlands

  • Harry J. M. Groen,

    Affiliation University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, the Netherlands

  • Wim Timens,

    Affiliation University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, the Netherlands

  • H. Marike Boezen,

    Affiliations University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands

  • Dirkje S. Postma ,

    d.s.postma@umcg.nl

    Affiliations University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, the Netherlands, University of Groningen, University Medical Center Groningen, GRIAC research institute, Groningen, the Netherlands

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