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Research Article

Study of Protein Haptenation by Amoxicillin Through the Use of a Biotinylated Antibiotic

  • Adriana Ariza,

    Affiliations: Department of Chemical and Physical Biology, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain, Research Laboratory Carlos Haya Hospital-IBIMA, Málaga, Spain

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  • Daniel Collado,

    Affiliations: Department of Organic Chemistry, University of Málaga, Malaga, Spain, BIONAND-Andalusian Centre for Nanomedicine and Biotechnology, Parque Tecnológico de Andalucía, Málaga, Spain

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  • Yolanda Vida,

    Affiliations: Department of Organic Chemistry, University of Málaga, Malaga, Spain, BIONAND-Andalusian Centre for Nanomedicine and Biotechnology, Parque Tecnológico de Andalucía, Málaga, Spain

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  • María I. Montañez,

    Affiliations: Research Laboratory Carlos Haya Hospital-IBIMA, Málaga, Spain, BIONAND-Andalusian Centre for Nanomedicine and Biotechnology, Parque Tecnológico de Andalucía, Málaga, Spain

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  • Ezequiel Pérez-Inestrosa,

    Affiliations: Department of Organic Chemistry, University of Málaga, Malaga, Spain, BIONAND-Andalusian Centre for Nanomedicine and Biotechnology, Parque Tecnológico de Andalucía, Málaga, Spain

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  • Miguel Blanca,

    Affiliation: Allergy Service, Hospital Carlos Haya, Málaga, Spain

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  • María José Torres,

    Affiliation: Research Laboratory Carlos Haya Hospital-IBIMA, Málaga, Spain

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  • F. Javier Cañada,

    Affiliation: Department of Chemical and Physical Biology, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain

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  • Dolores Pérez-Sala mail

    dperezsala@cib.csic.es

    Affiliation: Department of Chemical and Physical Biology, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain

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  • Published: March 03, 2014
  • DOI: 10.1371/journal.pone.0090891

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