Imaging Neuroinflammation In Vivo in a Neuropathic Pain Rat Model with Near-Infrared Fluorescence and 19F Magnetic Resonance

Kiran Vasudeva; Karl Andersen; Bree Zeyzus-Johns; T. Kevin Hitchens; Sravan Kumar Patel; Anthony Balducci; Jelena M. Janjic; John A. Pollock

doi:10.1371/journal.pone.0090589

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Peer-reviewed

Research Article

Imaging Neuroinflammation In Vivo in a Neuropathic Pain Rat Model with Near-Infrared Fluorescence and ¹⁹F Magnetic Resonance

Kiran Vasudeva,

Affiliation Biological Sciences, Bayer School of Natural and Environmental Sciences, and Chronic Pain Research Consortium, Duquesne University, Pittsburgh, Pennsylvania, United States of America
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Karl Andersen,

Affiliation Biological Sciences, Bayer School of Natural and Environmental Sciences, and Chronic Pain Research Consortium, Duquesne University, Pittsburgh, Pennsylvania, United States of America
⨯
Bree Zeyzus-Johns,

Affiliation Biological Sciences, Bayer School of Natural and Environmental Sciences, and Chronic Pain Research Consortium, Duquesne University, Pittsburgh, Pennsylvania, United States of America
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T. Kevin Hitchens,

Affiliation NMR Center for Biomedical Research, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
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Sravan Kumar Patel,

Affiliation Graduate School of Pharmaceutical Sciences, Mylan School of Pharmacy, and Chronic Pain Research Consortium, Duquesne University, Pittsburgh, Pennsylvania, United States of America
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Anthony Balducci,

Affiliation Department of Research and Development, Celsense, Inc., Pittsburgh, Pennsylvania, Unite States of America
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Jelena M. Janjic,

Affiliation Graduate School of Pharmaceutical Sciences, Mylan School of Pharmacy, and Chronic Pain Research Consortium, Duquesne University, Pittsburgh, Pennsylvania, United States of America
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John A. Pollock

* E-mail: pollock@duq.edu

Affiliation Biological Sciences, Bayer School of Natural and Environmental Sciences, and Chronic Pain Research Consortium, Duquesne University, Pittsburgh, Pennsylvania, United States of America
⨯

Imaging Neuroinflammation In Vivo in a Neuropathic Pain Rat Model with Near-Infrared Fluorescence and ¹⁹F Magnetic Resonance

Kiran Vasudeva,
Karl Andersen,
Bree Zeyzus-Johns,
T. Kevin Hitchens,
Sravan Kumar Patel,
Anthony Balducci,
Jelena M. Janjic,
John A. Pollock

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Published: February 28, 2014
https://doi.org/10.1371/journal.pone.0090589

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Sciatic nerves
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Near-infrared spectroscopy
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Magnetic resonance imaging
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Macrophages
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Fluorescence imaging
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Neuropathic pain
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In vivo imaging
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Inflammation
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