Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs

Eliska Potuckova; Hana Jansova; Miloslav Machacek; Anna Vavrova; Pavlina Haskova; Lucie Tichotova; Vera Richardson; Danuta S. Kalinowski; Des R. Richardson; Tomas Simunek

doi:10.1371/journal.pone.0088754

Loading metrics

Open Access

Peer-reviewed

Research Article

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs

Eliska Potuckova,

Affiliation Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Prague, Czech Republic
⨯
Hana Jansova,

Affiliation Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Prague, Czech Republic
⨯
Miloslav Machacek,

Affiliation Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Prague, Czech Republic
⨯
Anna Vavrova,

Affiliation Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Prague, Czech Republic
⨯
Pavlina Haskova,

Affiliation Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Prague, Czech Republic
⨯
Lucie Tichotova,

Affiliation Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Prague, Czech Republic
⨯
Vera Richardson,

Affiliation Molecular Pharmacology and Pathology Program, Bosch Institute and Department of Pathology, University of Sydney, Sydney, Australia
⨯
Danuta S. Kalinowski,

Affiliation Molecular Pharmacology and Pathology Program, Bosch Institute and Department of Pathology, University of Sydney, Sydney, Australia
⨯
Des R. Richardson ,

* E-mail: Tomas.Simunek@faf.cuni.cz (TS); d.richardson@med.usyd.edu.au (DRR)

Affiliation Molecular Pharmacology and Pathology Program, Bosch Institute and Department of Pathology, University of Sydney, Sydney, Australia
⨯
Tomas Simunek

* E-mail: Tomas.Simunek@faf.cuni.cz (TS); d.richardson@med.usyd.edu.au (DRR)

Affiliation Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Prague, Czech Republic
⨯

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs

Eliska Potuckova,
Hana Jansova,
Miloslav Machacek,
Anna Vavrova,
Pavlina Haskova,
Lucie Tichotova,
Vera Richardson,
Danuta S. Kalinowski,
Des R. Richardson,
Tomas Simunek

x

Published: February 20, 2014
https://doi.org/10.1371/journal.pone.0088754

Viewed

Cited

Saved

Discussed

Powered by Altmetric

Questions or concerns about usage data? Please let us know.

Print

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Estrogens
Is the Subject Area "Estrogens" applicable to this article?

Thanks for your feedback.
Chemotherapeutic agents
Is the Subject Area "Chemotherapeutic agents" applicable to this article?

Thanks for your feedback.
Computer software
Is the Subject Area "Computer software" applicable to this article?

Thanks for your feedback.
Cell cycle and cell division
Is the Subject Area "Cell cycle and cell division" applicable to this article?

Thanks for your feedback.
Membrane potential
Is the Subject Area "Membrane potential" applicable to this article?

Thanks for your feedback.
Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.